When the universe's highest-flying dogs warp into outer space, Skyfetcher and Spaceslobber get a call from canine headquarters! It seems an unknown force is attacking unsuspecting planets, and it's up to them to root out…

　Mac（黎明）、Bird（陈小春）、Sam（李灿森）和Michelle（雪儿）是国际神偷组织界的精英，四人一向合作无间配合默契，完成过许多艰巨任务。　　此次四人要到马来西亚侦察一名科学家，希望偷取其刚研制成功的治癌药。可是在悄悄潜入药厂…